• Product Name Ledipasvir (acetone)
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityLedipasvir (GS5885) is a HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.
• Target NameHCV Protease antagonist
• CAS No. 1441674-54-9
• Calculated MW 947.08
• Formulation C??H??F?N?O?
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:inflammation
  SMILES:CC(C)[C@@H](C(=O)N1CC2(CC2)C[C@H]1C3=NC=C(N3)C4=CC5=C(C=C4)C6=C(C5(F)F)C=C(C=C6)C7=CC8=C(C=C7)N=C(N8)[C@@H]9[C@H]1CC[C@H](C1)N9C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC.CC(=O)C
  Pathways:Microbiology&virology; Proteases/Proteasome
  Receptor:HCV
  Boling pt:
  Melting pt:
  Solubility:DMSO:100 mg/mL (112.48 mM)Ethanol:100 mg/mL (112.48 mM)Water<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Smith MA, et al. Ann Pharmacother. 2015 Mar;49(3):343-50.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting