• Product Name XMU-MP-1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityXMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50 values of 71.1 and 38.1 nM against MST1 and MST2.
• Target NameHippo pathway inhibitor
• CAS No. 2061980-01-4
• Calculated MW 416.474
• Formulation C17H16N6O3S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:O=S(C1=CC=C(NC2=NC=C3C(N(C)C(C=CS4)=C4C(N3C)=O)=N2)C=C1)(N)=O
  Pathways:Stem Cells
  Receptor:MST1; MST2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 30 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Fan F, et al. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration. Sci Transl Med. 2016 Aug 17;8(352):352ra108.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting