• Product NameKDM4D-IN-1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityKDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.410.03 μM.
• Target NameHistone Demethylase inhibitor
• CAS No. 2098902-68-0
• Calculated MW 225.21
• Formulation C11H7N5O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:OC1=NC2=C(C#N)C(C)=NN2C3=C1C=CC=N3
  Pathways:Chromatin/Epigenetic
  Receptor:KDM4D
  Boling pt:
  Melting pt:
  Solubility:DMSO: 6 mg/mL (Need ultrasonic)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Fang Z, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3201-3204.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting