• Product NameAmenamevir
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityAmenamevir(ASP2151) is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC50 of 14 ng/mL.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 841301-32-4
• Calculated MW 482.555
• Formulation C24H26N4O5S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:infection
  SMILES:CC1=C(C(=CC=C1)C)N(CC(=O)NC2=CC=C(C=C2)C3=NOC=N3)C(=O)C4CCS(=O)(=O)CC4
  Pathways:DNA Damage/DNA Repair
  Receptor:helicase-primase
  Boling pt:
  Melting pt:
  Solubility:DMSO: 160 mg/mL
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Katsumata K, et al. Pharmacokinetics and pharmacodynamics of ASP2151, a helicase-primase inhibitor, in a murine model of herpes simplex virus infection. Antimicrob Agents Chemother. 2013 Mar;57(3):1339-46.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting