• Product NameHJC0152
• Brief DescriptionInhibitors
• Purification98.33%
• Biological ActivityHJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor with remarkably improved aqueous solubility.
• Target NameSTAT inhibitor
• CAS No. 1420290-99-8
• Calculated MW 406.644
• Formulation C15H14Cl3N3O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)OCCN.Cl
  Pathways:JAK/STAT signaling; Stem Cells
  Receptor:STAT3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 88 mg/mL (216.4 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chen H, et al. Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents. ACS Med Chem Lett. 2013 Feb 14;4(2):180-185.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting