• Product NamehVEGF-IN-1
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityhVEGF-IN-1 represses human VEGF-A translation and shows antitumor activity.
• Target NameVEGFR inhibitor
• CAS No. 1637443-98-1
• Calculated MW 581.75
• Formulation C34H43N7O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CCN1CCN(CC1)CCCCN2C3=C(C=C(C=C3)C(=NOCC)C)C4=C2C5=C(C6=CN(N=C6CC5)C)C7=C(NC=C47)O
  Pathways:Angiogenesis; Tyrosine Kinase/Adaptors
  Receptor:VEGF-A
  Boling pt:
  Melting pt:
  Solubility:10 mM in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Discovery of Small Molecules for Repressing Cap-Independent Translation of Human VascularEndothelial Growth Factor (hVEGF) as Novel Antitumor Agents. J Med Chem. 2017 Jul 13;60(13):5306-5319.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting