• Product NameDCC-2618
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityDCC-2618 is a potent inhibitor of c-Kit and c-Met with IC50s of <200 nM.
• Target Namec-Kit inhibitor; c-Met/HGFR inhibitor
• CAS No. 1225278-16-9
• Calculated MW 489.47
• Formulation C26H21F2N5O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CN1C=C(C=N1)C2=NC=CC(=C2)OC3=C(C=C(C(=C3)F)NC(=O)C4(CC4)C(=O)NC5=CC=CC=C5)F
  Pathways:Tyrosine Kinase/Adaptors
  Receptor:c-Kit; c-Met
  Boling pt:
  Melting pt:
  Solubility:Soluble in DMSO
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities. WO 2010051373 A1

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting