• Product NameEnzalutamide (MDV3100)
• Brief DescriptionInhibitors
• Purification99.67%
• Biological ActivityEnzalutamide (MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM.
• Target NameAndrogen Receptor antagonist
• CAS No. 915087-33-1
• Calculated MW 464.44
• Formulation C21H16F4N4O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CNC(=O)C1=C(F)C=C(C=C1)N1C(=S)N(C(=O)C1(C)C)C1=CC(=C(C=C1)C#N)C(F)(F)F
  Pathways:Endocrinology/Hormones
  Receptor:Androgen Receptor
  Boling pt:
  Melting pt:
  Solubility:DMSO: 92 mg/mL warmed (198.08 mM)
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Tran C, et al, Science, 2009, 324 (5928), 787-790.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting