• Product NameRomidepsin (FK228, Depsipeptide)
• Brief DescriptionInhibitors
• Purification99.67%
• Biological ActivityRomidepsin (FK228, depsipeptide) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.
• Target NameHDAC inhibitor
• CAS No. 128517-07-7
• Calculated MW 540.7
• Formulation C24H36N4O6S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC=C1NC(=O)C2CSSCCC=CC(CC(=O)NC(C(C)C)C(=O)N2)OC(=O)C(NC1=O)C(C)C
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC1; HDAC2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 10 mg/mL (18.49 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Furumai R, et al. Y Res, 2002, 62(17), 4916-4921.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting