• Product NameIdarubicin HCl
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityIdarubicin HCl is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL.
• Target NameOthers inhibitor; Topoisomerase inhibitor
• CAS No. 57852-57-0
• Calculated MW 533.95
• Formulation C26H27NO9.HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=CC=CC=C5C4=O)O)(C(=O)C)O)N)O.Cl
  Pathways:DNA Damage/DNA Repair; Others
  Receptor:Multicellular spheroids; Topo II (MCF-7 cells)
  Boling pt:
  Melting pt:
  Solubility:DMSO:100 mg/mL (187.28 mM)Ethanol:<1 mg/mL (<1 mM)Water:7 mg/mL warmed (13.1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Orlandi P, et al. J Chemother. 2005, 17(6), 663-667.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting