• Product NameBatimastat (BB-94)
• Brief DescriptionInhibitors
• Purification99.50%
• Biological ActivityBatimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3 with IC50 of 3 nM, 4 nM, 4 nM, 6 nM and 20 nM, respectively. Also inhibits the activitity of other metalloproteases, such as ADAM17.
• Target NameMMP inhibitor
• CAS No. 130370-60-4
• Calculated MW 477.64
• Formulation C23H31N3O4S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(C)C)[C@H](CSC1=CC=CS1)C(=O)NO |r,c:8,10,26,t:6,24|
  Pathways:Proteases/Proteasome
  Receptor:MMP-1; MMP-2; MMP-3; MMP-7; MMP-9
  Boling pt:
  Melting pt:
  Solubility:DMSO:96 mg/mL (200.98 mM)Ethanol:<1 mg/mL (<1 mM)Water<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Chirivi RG, et al. Int J Cancer, 1994, 58(3), 460-464.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting