• Product NameZ-VAD-FMK
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityZ-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor, blocks all features of apoptosis.
• Target NameCaspase inhibitor
• CAS No. 187389-52-2
• Calculated MW 467.49
• Formulation C22H30FN3O7
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C[C@@H](C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1
  Pathways:Apoptosis; Proteases/Proteasome
  Receptor:Pan-caspase
  Boling pt:
  Melting pt:
  Solubility:DMSO: 93 mg/mL (198.93 mM)
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Slee EA, et al. Biochem J, 1996, 315 (Pt 1), 21-24.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting