• Product NameMaraviroc
• Brief DescriptionInhibitors
• Purification100.00%
• Biological ActivityMaraviroc is a CCR5 antagonist for MIP-1α, MIP-1β and RANTES with IC50 of 3.3 nM, 7.2 nM and 5.2 nM, respectively.
• Target NameCCR antagonist
• CAS No. 376348-65-1
• Calculated MW 513.67
• Formulation C29H41F2N5O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC1=NN=C(N1C2C[C@H]3CC[C@@H](C2)N3CC[C@@H](C4=CC=CC=C4)NC(=O)C5CCC(CC5)(F)F)C(C)C
  Pathways:Immunology/Inflammation; Microbiology&virology
  Receptor:MIP-1α; MIP-1β; RANTES
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 100 mg/mL (194.67 mM); DMSO: 100 mg/mL (194.67 mM)
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Dorr P, et al. Antimicrob Agents ChemOthers. 2005, 49(11), 4721-4732.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting