• Product NameUMI-77
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityUMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family.
• Target NameBCL inhibitor
• CAS No. 518303-20-3
• Calculated MW 468.34
• Formulation C18H14BrNO5S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:OC(=O)CSC1=C(O)C2=CC=CC=C2C(NS(=O)(=O)C2=CC=C(Br)C=C2)=C1
  Pathways:Apoptosis
  Receptor:Mcl-1
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 93 mg/mL warmed (198.57 mM); DMSO: 93 mg/mL (198.57 mM)
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Abulwerdi F, et al. Mol Y Ther. 2014, 13(3), 565-575.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting