Research Area:Cancer
SMILES:CC(C)(O)CC(=O)NCCN1C=CC2=C1C(NC1=CC=C(OC3=CC=CC(=C3)C(F)(F)F)C(Cl)=C1)=NC=N2 |c:11,13,25,27,35,37,39,t:18,20,23|
Pathways:Angiogenesis; Cell Cycle/Checkpoint; MAPK; Chromatin/Epigenetic; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Receptor:Aurora B; EGFR/HER1; HER2; HER4; MEK1
Boling pt:
Melting pt:
Solubility:DMSO:110 mg/mL (200.74 mM)Ethanol:54 mg/mL (98.54 mM)Water:<1 mg/mL (<1 mM)
Appearance:
Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.