• Product NamePF-2545920
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityPF-2545920 is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM, with >1000-fold selectivity over the PDE.
• Target NamePDE inhibitor
• CAS No. 1292799-56-4
• Calculated MW 392.45
• Formulation C25H20N4O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CN1C=C(C(=N1)C2=CC=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)C5=CC=NC=C5
  Pathways:Metabolism
  Receptor:PDE10A
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 79 mg/mL (201.29 mM); DMSO: 79 mg/mL (201.29 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Wilson JM, et al. Neuropharmacology. 2015 Dec;99:379-86.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting