• Product NameBrefeldin A
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityBrefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces Y cell differentiation and apoptosis.
• Target NameATPase inhibitor
• CAS No. 20350-15-6
• Calculated MW 280.36
• Formulation C16H24O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:C[C@H]1CCC/C=C/[C@@H]2C[C@@H](C[C@H]2[C@@H](/C=C/C(=O)O1)O)O
  Pathways:Membrane transporter/Ion channel
  Receptor:ATPase (HCT 116)
  Boling pt:
  Melting pt:
  Solubility:DMSO: 4 mg/mL (14.26 mM)
  Appearance:Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zhu JW, et al. Bioorg Med Chem. 2000, 8(2), 455-463.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting