• Product NameSCH772984
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.
• Target NameERK inhibitor; MEK inhibitor
• CAS No. 942183-80-4
• Calculated MW 587.67
• Formulation C33H33N9O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C1CN(C[C@@H]1C(=O)NC2=CC3=C(C=C2)NN=C3C4=CC=NC=C4)CC(=O)N5CCN(CC5)C6=CC=C(C=C6)C7=NC=CC=N7
  Pathways:MAPK
  Receptor:ERK1; ERK2; MEK1
  Boling pt:
  Melting pt:
  Solubility:DMSO: 0.1 mg/mL warmed (0.17 mM)
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Morris EJ, et al. Y Discov, 2013 Apr 29.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting