• Product NameGemcitabine HCl
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityGemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.
• Target NameDNA/RNA Synthesis inhibitor
• CAS No. 122111-03-9
• Calculated MW 299.66
• Formulation C9H11F2N3O4.HCI
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:Cl.NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F |r,c:6,t:1|
  Pathways:DNA Damage/DNA Repair
  Receptor:DNA synthesis (BxPC3 cells); DNA synthesis (Capan2 cells); DNA synthesis (MIAPaCa2 cells); DNA synthesis (PANC1 cells)
  Boling pt:
  Melting pt:
  Solubility:DMSO:<1 mg/mL (<1 mM)Ethanol:<1 mg/mL (<1 mM)Water19 mg/mL (63.4 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Shi X, et al. Oncology. 2002, 62(4), 354-362.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting