• Product NameIU1
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityIU1 is a cell-permeable, reversible and selective proteasome inhibitor of human USP14 with IC50 of 4.7 μ M, 25-fold selective to IsoT.
• Target NameDUB inhibitor
• CAS No. 314245-33-5
• Calculated MW 300.37
• Formulation C18H21FN2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Others
  SMILES:CC1=CC(C(=O)CN2CCCC2)=C(C)N1C1=CC=C(F)C=C1
  Pathways:Ubiquitination
  Receptor:USP14
  Boling pt:
  Melting pt:
  Solubility:DMSO:60 mg/mL (199.75 mM)Ethanol:60 mg/mL (199.75 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Byung-Hoon L, et al. Nature, 2010, 467(7312), 179-184.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting