• Product NameSkepinone-L
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySkepinone-L is a selective p38α-MAPK inhibitor with IC50 of 5 nM.
• Target Namep38 MAPK inhibitor
• CAS No. 1221485-83-1
• Calculated MW 425.42
• Formulation C24H21F2NO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:OC[C@@H](O)COC1=CC=C2CCC3=CC(NC4=CC=C(F)C=C4F)=CC=C3C(=O)C2=C1 |r,c:21,24,26,32,t:6,8,12,16,18|
  Pathways:MAPK
  Receptor:p38α
  Boling pt:
  Melting pt:
  Solubility:DMSO:85 mg/mL (199.8 mM)Ethanol:85 mg/mL (199.8 mM)Water<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Koeberle SC, et al. Nat Chem Biol. 2011, 8(2), 141-143.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting