• Product NameOctanoic acidCPI-613
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityCPI-613, a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. Phase 2.
• Target NameDehydrogenase inhibitor
• CAS No. 95809-78-2
• Calculated MW 388.59
• Formulation C22H28O2S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:OC(=O)CCCCC(CCSCC1=CC=CC=C1)SCC1=CC=CC=C1 |c:14,16,23,25,t:12|
  Pathways:Metabolism
  Receptor:α-ketoglutarate dehydrogenase; PDH
  Boling pt:
  Melting pt:
  Solubility:DMSO:78 mg/mL (200.72 mM)Ethanol:78 mg/mL (200.72 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zachar Z, et al. J Mol Med (Berl). 2011, 89(11), 1137-1148.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting