• Product NameSalirasib
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivitySalirasib is a potent competitive prenylated protein methyltransferase (PPMTase) inhibitor with Ki of 2.6 μM, which inhibits Ras methylation. Phase 2.
• Target NameRas inhibitor
• CAS No. 162520-00-5
• Calculated MW 358.54
• Formulation C22H30O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC(=CCC/C(=C/CC/C(=C/CSC1=CC=CC=C1C(=O)O)/C)/C)C
  Pathways:MAPK
  Receptor:PPMTase
  Boling pt:
  Melting pt:
  Solubility:DMSO>10mMN/AN/A
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Marciano D, et al. J Med Chem. 1995, 38(8), 1267-1272.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting