• Product NameBardoxolone Methyl
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityBardoxolone Methyl is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities. Phase 3.
• Target NameIκB/IKK inhibitor
• CAS No. 218600-53-4
• Calculated MW 505.69
• Formulation C32H43NO4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C[C@@]12CC[C@]3(CCC(C[C@H]3[C@H]1C(=O)C=C4[C@]2(CC[C@@H]5[C@@]4(C=C(C(=O)C5(C)C)C#N)C)C)(C)C)C(=O)OC
  Pathways:NF-κb
  Receptor:IKK
  Boling pt:
  Melting pt:
  Solubility:DMSO:21 mg/mL (41.52 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Honda T, et al. J Med Chem. 2000, 43(22), 4233-4246.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting