• Product NameMRS 2578
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityMRS2578 is a potent P2Y6 receptor antagonist with IC50 of 37 nM, exhibits insignificant activity at P2Y1, P2Y2, P2Y4,and P2Y11 receptors.
• Target NameP2 Receptor antagonist
• CAS No. 711019-86-2
• Calculated MW 472.67
• Formulation C20H20N6S4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:S=C=NC1=CC=CC(NC(=S)NCCCCNC(=S)NC2=CC(=CC=C2)N=C=S)=C1 |c:5,22,24,29,t:3,20|
  Pathways:Neuroscience
  Receptor:P2Y6
  Boling pt:
  Melting pt:
  Solubility:DMSO:42 mg/mL (88.85 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Mamedova LK, et al. Biochem Pharmacol, 2004, 67(9), 1763-1770.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting