• Product NameADL5859 HCl
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityADL5859 HCl is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel. Phase 2.
• Target NameOpioid Receptor agonist
• CAS No. 850173-95-4
• Calculated MW 428.95
• Formulation C24H28N2O3.HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:Cl.CCN(CC)C(=O)C1=CC=C(C=C1)C1=CC2(CCNCC2)OC2=CC=CC(O)=C12 |c:9,11,26,t:7,14,24,29|
  Pathways:Endocrinology/Hormones; GPCR/G Protein; Neuroscience
  Receptor:δ-opioid receptor; κ-opioid receptor; μ-opioid receptor
  Boling pt:
  Melting pt:
  Solubility:DMSO:86 mg/mL (200.48 mM)Ethanol:1 mg/mL (2.33 mM)Water:5 mg/mL (11.65 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Le Bourdonnec B, et al. J Med Chem, 2008, 51(19), 5893-5896.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting