• Product NameTDZD-8
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityTDZD-8 is a non-ATP competitive GSK-3β inhibitor with IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.
• Target NameGSK-3 inhibitor
• CAS No. 327036-89-5
• Calculated MW 222.26
• Formulation C10H10N2O2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CN1SC(=O)N(CC2=CC=CC=C2)C1=O
  Pathways:PI3K/Akt/mTOR signaling; Stem Cells
  Receptor:GSK-3β
  Boling pt:
  Melting pt:
  Solubility:DMSO:44.5 mg/mL (200.21 mM)Ethanol:44.5 mg/mL (200.21 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Martinez A, et al. J Med Chem, 2002, 45(6), 1292-1299.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting