• Product NamePJ34
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityPJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
• Target NamePARP inhibitor
• CAS No. 344458-19-1
• Calculated MW 295.34
• Formulation C17H17N3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CN(C)CC(=O)NC1=CC2=C(NC(=O)C3=CC=CC=C23)C=C1
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair
  Receptor:PARP1; PARP2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 66 mg/mL (198.91 mM)
  Appearance:YellowPowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Garcia Soriano F, et al. Nat Med, 2001, 7(1), 108-113.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting