• Product NameCW069
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCW069 is an allosteric, and selective inhibitor of microtubule motor protein HSET with IC50 of 75 μM, significant selectivity over KSP.
• Target NameMicrotubule Associated inhibitor
• CAS No. 1594094-64-0
• Calculated MW 500.33
• Formulation C23H21IN2O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:O=C(O)C1=CC(I)=CC=C1NC([C@@H](NCC2=CC=CC=C2)CC3=CC=CC=C3)=O
  Pathways:Cytoskeletal Signaling
  Receptor:HSET
  Boling pt:
  Melting pt:
  Solubility:DMSO 100 mg/mL(199.86 mM)Ethanol 4 mg/mL(7.99 mM)Water <1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Watts CA, et al. Chem Biol. 2013, 20(11), 1399-1410.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting