• Product NamePifithrin-μ
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityPifithrin-μ is a specific p53 inhibitor by reducing its affinity to Bcl-xL and Bcl-2, and also inhibits HSP70 function and autophagy.
• Target Namep53 inhibitor
• CAS No. 64984-31-2
• Calculated MW 181.21
• Formulation C8H7NO2S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:NS(=O)(=O)C#CC1=CC=CC=C1 |c:8,10,t:6|
  Pathways:Apoptosis
  Receptor:p53
  Boling pt:
  Melting pt:
  Solubility:DMSO:36 mg/mL (198.66 mM)Ethanol:36 mg/mL (198.66 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Strom E, et al. Nat Chem Biol. 2006, 2(9), 474-479.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting