• Product NameCombretastatin A4
• Brief DescriptionInhibitors
• Purification99.81%
• Biological ActivityCombretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.Phase 3.
• Target NameMicrotubule Associated inhibitor
• CAS No. 117048-59-6
• Calculated MW 316.35
• Formulation C18H20O5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:COC1=C(C=C(C=C1)/C=C\C2=CC(=C(C(=C2)OC)OC)OC)O
  Pathways:Cytoskeletal Signaling
  Receptor:Tubulin β
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 34 mg/mL warmed (107.47 mM); DMSO: 63 mg/mL (199.14 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Zheng S, et al. J Med Chem. 2014, 57(8), 3369-3381.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting