• Product NameLFM-A13
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityLFM-A13 is a specific Bruton's tyrosine kinase (BTK) with IC50 of 2.5 μM, >100-fold selectivity over other protein kinases including JAK1, JAK2, HCK, EGFR,and IRK.
• Target NameBTK inhibitor
• CAS No. 244240-24-2
• Calculated MW 360
• Formulation C11H8Br2N2O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C/C(=C(\C#N)/C(=O)NC1=C(C=CC(=C1)Br)Br)/O
  Pathways:Angiogenesis
  Receptor:BTK
  Boling pt:
  Melting pt:
  Solubility:DMSO:72 mg/mL warmed (200.0 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Mahajan S, et al. J Biol Chem. 1999, 274(14), 9587-9599.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting