• Product NameAmbroxol hydrochloride
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityAmbroxol HCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. Phase 3.
• Target NameSodium Channel inhibitor
• CAS No. 23828-92-4
• Calculated MW 414.56
• Formulation C13H18Br2N2OHCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:Cl.NC1=C(Br)C=C(Br)C=C1CNC1CCC(O)CC1
  Pathways:Membrane transporter/Ion channel
  Receptor:Sodium Channel
  Boling pt:
  Melting pt:
  Solubility:DMSO: 3 mg/mL (7.23 mM)
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Weiser T, et al. Mol Pharmacol, 2002, 62(3), 433-438.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting