• Product NameRupatadine Fumarate
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityRupatadine is an inhibitor of PAFR and histamine (H1) receptor with Ki of 550 nM and 102 nM, respectively.
• Target NameHistamine Receptor inhibitor; PAFR inhibitor
• CAS No. 182349-12-8
• Calculated MW 532.03
• Formulation C26H26ClN3C4H4O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Nervous system
  SMILES:CC1=CC(=CN=C1)CN2CCC(=C3C4=C(CCC5=C3N=CC=C5)C=C(C=C4)Cl)CC2.C(=C/C(=O)O)\C(=O)O
  Pathways:GPCR/G Protein; Immunology/Inflammation; Neuroscience
  Receptor:H1 receptor; PAFR
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 13 mg/mL (24.43 mM); DMSO: 9 mg/mL (16.91 mM)
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Merlos M, et al. J Pharmacol Exp Ther, 1997, 280(1), 114-121.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting