• Product NameIdasanutlin (RG-7388)
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityIdasanutlin (RG-7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM.
• Target NameMdm2 inhibitor
• CAS No. 1229705-06-9
• Calculated MW 616.48
• Formulation C31H29Cl2F2N3O4
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:CC(C)(C)C[C@H]1[C@]([C@H]([C@@H](N1)C(=O)NC2=C(C=C(C=C2)C(=O)O)OC)C3=C(C(=CC=C3)Cl)F)(C#N)C4=C(C=C(C=C4)Cl)F
  Pathways:Apoptosis
  Receptor:Mdm2
  Boling pt:
  Melting pt:
  Solubility:DMSO:100 mg/mL (162.21 mM)Ethanol:8 mg/mL warmed (12.97 mM)Water<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Ding Q, et al. J Med Chem. 2013, 56(14), 5979-5983.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting