• Product NameCP-466722
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityCP-466722 is a potent and reversible ATM inhibitor, does not affect ATR and inhibits PI3K or PIKK family members in cells.
• Target NameATM/ATR inhibitor
• CAS No. 1080622-86-1
• Calculated MW 349.35
• Formulation C17H15N7O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:COC1=C(OC)C=C2C(=C1)N=CN=C2N1N=C(N=C1N)C1=CC=CC=N1
  Pathways:DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
  Receptor:ATM
  Boling pt:
  Melting pt:
  Solubility:DMSO: 0.28 mg/mL (0.8 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Rainey MD, et al. Y Res, 2008, 68(18), 7466-7474.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting