• Product NameLomitapide
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityLomitapide is a potent microsomal triglyceride transfer protein (MTP) inhibitor, used in the treatment of familial hypercholesterolemia.
• Target NameCETP inhibitor
• CAS No. 182431-12-5
• Calculated MW 692.71
• Formulation C39H37F6N3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Other
  SMILES:FC(F)(F)CNC(=O)C1(CCCCN2CCC(CC2)NC(=O)C2=C(C=CC=C2)C2=CC=C(C=C2)C(F)(F)F)C2=C(C=CC=C2)C2=C1C=CC=C2 |c:25,27,32,34,43,45,48,51,53,t:23,30,41|
  Pathways:Metabolism
  Receptor:MTP
  Boling pt:
  Melting pt:
  Solubility:DMSO:100 mg/mL (144.36 mM)Ethanol:100 mg/mL warmed (144.36 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Davis KA, Miyares MA. Am J Health Syst Pharm. 2014 Jun 15;71(12):1001-8.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting