• Product NameTrichostatin A (TSA)
• Brief DescriptionInhibitors
• Purification99.02%
• Biological ActivityTrichostatin A (TSA) is an HDAC inhibitor with IC50 of ~1.8 nM C HDAC8 is the only known member of the HDAC-family that is not affected by TSA.
• Target NameHDAC inhibitor
• CAS No. 58880-19-6
• Calculated MW 302.4
• Formulation C17H22N2O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC
  Boling pt:
  Melting pt:
  Solubility:DMSO:23 mg/mL (76.05 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:Brown powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Vigushin DM, et al. Clin Y Res, 2001, 7(4), 971-976.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting