• Product NameTariquidar
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityTariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM, reverses drug resistance in MDR cell Lines. Phase 3.
• Target NameP-gp inhibitor
• CAS No. 206873-63-4
• Calculated MW 646.73
• Formulation C38H38N4O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:COC1=CC2=C(CN(CCC3=CC=C(NC(=O)C4=C(NC(=O)C5=CC6=CC=CC=C6N=C5)C=C(OC)C(OC)=C4)C=C3)CC2)C=C1OC |c:17,26,28,31,40,43,49,t:2,4,10,12,22,24,34|
  Pathways:Membrane transporter/Ion channel; Neuroscience
  Receptor:P-gp?(P-glycoprotein)
  Boling pt:
  Melting pt:
  Solubility:DMSO:52 mg/mL (80.4 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Martin C, et al. Br J Pharmacol, 1999, 128(2), 403-411.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting