• Product NameStattic
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityStattic, the first nonpeptidic small molecule, potently inhibits STAT3 activation and nuclear translocation with IC50 of 5.1 μM, highly selectivity over STAT1.
• Target NameSTAT inhibitor
• CAS No. 19983-44-9
• Calculated MW 211.19
• Formulation C8H5NO4S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:[O-][N+](=O)C1=CC2=C(C=CS2(=O)=O)C=C1
  Pathways:JAK/STAT signaling; Stem Cells
  Receptor:STAT3
  Boling pt:
  Melting pt:
  Solubility:DMSO: 42 mg/mL (198.87 mM)
  Appearance:Orange Powder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Schust J, et al. Chem Biol, 2006, 13(11), 1235-1242.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting