• Product NameGW3965 HCl
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityGW3965 HCl is a potent, selective LXR agonist for hLXRα and hLXRβ with EC50 of 190 and 30 nM, respectively.
• Target NameLiver X Receptor agonist
• CAS No. 405911-17-3
• Calculated MW 618.51
• Formulation C33H31ClF3NO3.HCl
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:Cl.OC(=O)CC1=CC=CC(OCCCN(CC(C2=CC=CC=C2)C2=CC=CC=C2)CC2=CC=CC(=C2Cl)C(F)(F)F)=C1 |c:6,18,20,25,27,33,35,42,t:4,16,23,31|
  Pathways:Others
  Receptor:hLXRα; hLXRβ; LXRα/SRC1?LiSA
  Boling pt:
  Melting pt:
  Solubility:DMSO:16 mg/mL warmed (25.86 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Collins JL, et al. J Med Chem. 2002, 45(10), 1963-1966.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting