• Product NameBMS-345541
• Brief DescriptionInhibitors
• Purification98.00%
• Biological ActivityBMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
• Target NameIκB/IKK inhibitor
• CAS No. 445430-58-0
• Calculated MW 255.32
• Formulation C14H17N5
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Immunology
  SMILES:CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN
  Pathways:NF-κb
  Receptor:IKK1; IKK2
  Boling pt:
  Melting pt:
  Solubility:DMSO: 9 mg/mL (35.24 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Burke JR, et al. J Biol Chem, 2003, 278(3), 1450-1456.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting