• Product NameINO-1001
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityINO-1001 is a potent inhibitor of PARP with IC50 of <50 nM in CHO cells and a mediator of oxidant-induced myocyte dysfunction during reperfusion. Phase 2.
• Target NamePARP inhibitor
• CAS No. 3544-24-9
• Calculated MW 136.15
• Formulation C7H8N2O
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:NC(=O)C1=CC(N)=CC=C1
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair
  Receptor:PARP
  Boling pt:
  Melting pt:
  Solubility:DMSO:27 mg/mL (198.31 mM)Ethanol:27 mg/mL (198.31 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Brock WA, et al. Y Lett. 2004, 205(2), 155-160.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting