• Product NameGeldanamycin
• Brief DescriptionInhibitors
• Purification98.83%
• Biological ActivityGeldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM, specifically disrupts glucocorticoid receptor (GR)/HSP association.
• Target NameHSP inhibitor; Tyrosine Kinases inhibitor
• CAS No. 30562-34-6
• Calculated MW 560.64
• Formulation C29H40N2O9
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\C=C(\C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)/C)OC)OC(=O)N)\C)C)O)OC
  Pathways:Cytoskeletal Signaling; Proteases/Proteasome; Metabolism
  Receptor:HSP90; HSP90; p185
  Boling pt:
  Melting pt:
  Solubility:DMSO:50 mg/mL warmed (89.18 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Roe SM, et al, J Med Chem, 1999, 42(2), 260-266.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting