• Product NameAGK2
• Brief DescriptionInhibitors
• Purification98.68%
• Biological ActivityAGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM.
• Target NameSirtuin inhibitor
• CAS No. 304896-28-4
• Calculated MW 434.27
• Formulation C23H13Cl2N3O2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C1=CC2=C(C=CC=N2)C(=C1)NC(=O)/C(=C/C3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)/C#N
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair
  Receptor:SIRT2
  Boling pt:
  Melting pt:
  Solubility:DMSO:10 mg/mL warmed (23.02 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Outeiro TF, et al. Science.?007, 317(5837), 516-519.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting