• Product NameAR-42
• Brief DescriptionInhibitors
• Purification98.96%
• Biological ActivityAR-42 is an HDAC inhibitor with IC50 of 30 nM. Phase 1.
• Target NameHDAC inhibitor
• CAS No. 935881-37-1
• Calculated MW 312.36
• Formulation C18H20N2O3
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:cancer
  SMILES:CC(C)[C@H](C(=O)NC1=CC=C(C=C1)C(=O)NO)C1=CC=CC=C1 |r,c:9,11,20,22,t:7,18|
  Pathways:Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κb
  Receptor:HDAC
  Boling pt:
  Melting pt:
  Solubility:DMSO:63 mg/mL (201.69 mM)Ethanol:63 mg/mL (201.69 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Lu Q, et al. J Med Chem, 2005, 48(17), 5530-5535.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting