• Product NameAZD1981
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityAZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. Phase 2.
• Target NameGPR antagonist
• CAS No. 802904-66-1
• Calculated MW 388.87
• Formulation C19H17ClN2O3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Endocrine system
  SMILES:CC(=O)NC1=C2C(=CC=C1)N(CC(O)=O)C(C)=C2SC1=CC=C(Cl)C=C1 |c:6,8,17,26,t:4,21,23|
  Pathways:Endocrinology/Hormones
  Receptor:CRTh2 (DP2) receptor
  Boling pt:
  Melting pt:
  Solubility:DMSO:11 mg/mL (28.28 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Luker T, et al. Bioorg Med Chem Lett. 2011, 21(21), 6288-6292.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting