• Product NameCAY10505
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityCAY10505 is dehydroxyl of AS-252424, which is a PI3Kγ inhibitor with IC50 of 33 nM.
• Target NamePI3K inhibitor
• CAS No. 1218777-13-9
• Calculated MW 289.28
• Formulation C14H8FNO3S
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cancer
  SMILES:C1=CC(=CC=C1C2=CC=C(O2)/C=C/3\C(=O)NC(=O)S3)F
  Pathways:PI3K/Akt/mTOR signaling
  Receptor:PI3Kγ
  Boling pt:
  Melting pt:
  Solubility:DMSO: 58 mg/mL (200.49 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1.Tyagi S, Sharma S, Budhiraja RD.Can J Physiol Pharmacol. 2012 Jul;90(7):881-5.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting