• Product NameClinofibrate
• Brief DescriptionInhibitors
• Purification99.84%
• Biological ActivityClinofibrate inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR) with IC50 of 0.47 mM, is a lipid-lowering agent used for controlling high cholesterol and triacylglyceride levels in the blood.
• Target NameHMG-CoA Reductase inhibitor
• CAS No. 30299-08-2
• Calculated MW 468.58
• Formulation C28H36O6
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Metabolism system
  SMILES:CCC(C)(OC1=CC=C(C=C1)C1(CCCCC1)C1=CC=C(OC(C)(CC)C(O)=O)C=C1)C(O)=O
  Pathways:Metabolism
  Receptor:HMGCR
  Boling pt:
  Melting pt:
  Solubility:Ethanol: 94 mg/mL (200.6 mM); DMSO: 94 mg/mL (200.6 mM)
  Appearance:WhitePowder
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Matsuura K, et al, J Pharmacol Exp Ther, 1998, 285(3), 1096-1103.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting