• Product NameDofetilide
• Brief DescriptionInhibitors
• Purification99.00%
• Biological ActivityDofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug
• Target NamePotassium Channel inhibitor
• CAS No. 115256-11-6
• Calculated MW 441.56
• Formulation C19H27N3O5S2
• Storage 3 years -20˚C powder;2 years -80˚C in solvent;

• Research Area:Cardiovascular System
  SMILES:CN(CCOC1=CC=C(NS(C)(=O)=O)C=C1)CCC1=CC=C(NS(C)(=O)=O)C=C1 |c:14,28,t:5,7,19,21|
  Pathways:Membrane transporter/Ion channel
  Receptor:Potassium Channel
  Boling pt:
  Melting pt:
  Solubility:DMSO:88 mg/mL warmed (199.29 mM)Ethanol:<1 mg/mL (<1 mM)Water:<1 mg/mL (<1 mM)
  Appearance:
  Remark:For obtaining a higher solubility , please warm the tube at 37 ˚C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ˚C for several month.

1. Kiehn J, et al. Circulation, 1996, 94(10), 2572-2579.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting